Table S7.

Multivariable analyses of event-free survival according to the EGFL7 risk group in 126 older patients (age ≥60 y) with de novo CN-AML

Variables considered	EFS
	HR (95% CI)	P	HR (95% CI)	P	HR (95% CI)	P
EGFL7 risk group, favorable vs. unfavorable	0.48 (0.31–0.77)	0.002	0.44 (0.28–0.70)	<0.001	0.46 (0.29–0.72)	<0.001
WBC count, continuous	1.22 (1.05–1.40)	0.007	1.20 (1.04–1.39)	0.01	1.17 (1.01–1.36)	0.04
miR-155, high vs. low*	1.68 (1.14–2.47)	0.008	—	—	—	—
Platelets, continuous	—	—	1.16 (1.04–1.28)	0.006	—	—
Extramedullary involvement, present vs. absent	—	—	—	—	1.63 (1.05–2.53)	0.03

HRs greater than (or less than) 1.0 indicate higher (or lower) failure to achieve complete remission, relapse, or death (EFS) for the higher value of the continuous variables and the first category listed for the categorical variables.

^*The median expression value was used as the cut point.