Table 1.

Multivariable analyses of outcome according to the EGFL7 risk group in 126 older patients (age ≥60 y) with de novo CN-AML

Variables in final models	DFS		OS
	HR (95% CI)	P	HR (95% CI)	P
EGFL7 risk group, favorable vs. unfavorable	0.57 (0.34–0.95)	0.03	0.45 (0.29–0.71)	<0.001
Extramedullary involvement, present vs. absent	1.99 (1.13–3.51)	0.02	—	—
miR-155, high vs. low*	—	—	2.47 (1.65–3.70)	<0.001
Platelets, continuous	—	—	1.22 (1.09–1.36)	<0.001

Hazard ratios (HR) greater than (or less than) 1.0 indicate higher (or lower) risk for relapse or death (in DFS) or for death (in OS) for the higher value of the continuous variables and for the first category listed in the categorical variables.

^*The median expression value was used as the cut point.