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. 2017 May 22;114(23):6116–6121. doi: 10.1073/pnas.1619424114

Fig. S7.

Fig. S7.

MPIOs-αP-selectin–induced hyposignal predicts remission in PLP-induced EAE. (A) Experimental design. (B) Representative high-resolution T2*-weighted images after MPIOs-αP-selectin injection from PLP-induced EAE mice with deficits (first relapse, D15). Yellow arrows indicate signal voids. (C) Corresponding signal void quantification. #P < 0.05. n = 4 per group. (D) Clinical score analysis of P-selectin-high (blue line) or -low mice (yellow line) the day of MRI acquisition (day 15) and the day after (D16) (n = 4 per group) #P < 0.05. (E) Schematic representation of the main findings. See Table S1 for detailed sample size.