Table 2.
Characteristics of FFR-assessed lesions
| Variables | All lesions (n=185) | FFR >0.8 (n=82) | FFR ≤0.8 (n=103) | P |
|---|---|---|---|---|
| Lesion location | ||||
| LAD, n (%) | 125 (67.6) | 52 (63.4) | 73 (70.9) | 0.282 |
| LCX, n (%) | 32 (17.3) | 17 (20.7) | 15 (14.6) | 0.365 |
| RCA, n (%) | 23 (12.4) | 10 (12.2) | 13 (12.6) | 1.0 |
| Other (diagonal, OM, PDA), n (%) | 5 (2.7) | 3 (3.7) | 2 (1.9) | 0.657 |
| Lesion location in coronary arteries | ||||
| Proximal, n (%) | 84 (45.4) | 32 (39.0) | 52 (50.5) | 0.120 |
| Mid, n (%) | 94 (50.8) | 45 (54.9) | 49 (47.6) | 0.323 |
| Distal, n (%) | 7 (3.8) | 5 (6.1) | 2 (1.9) | 0.244 |
| QCA analysis | ||||
| Percent diameter stenosis, % | 54.4±4.1 | 53.7±4.0 | 54.9±4.1 | 0.053 |
| MLD, mm | 1.49 (1.09–1.49) | 1.45 (1.01–1.55) | 1.49 (1.09–1.49) | 0.005 |
| MLD <1.1 mm, n (%) | 35 (18.9) | 11 (13.4) | 24 (23.3) | 0.088 |
| MLD 1.1–1.5 mm, n (%) | 107 (57.8) | 30 (36.6) | 77 (74.8) | <0.001 |
| MLD >1.5 mm, n (%) | 43 (23.2) | 41 (50.0) | 2 (1.9) | <0.001 |
| LL, mm | 14 (9–19) | 10 (8–15) | 14 (11–20) | <0.001 |
| LL >18 mm, n (%) | 53 (28.6) | 15 (18.3) | 38 (36.9) | 0.005 |
| LL 9–18 mm, n (%) | 89 (48.1) | 33 (40.2) | 56 (54.4) | 0.056 |
| LL <9 mm, n (%) | 43 (23.2) | 34 (41.5) | 9 (8.7) | <0.001 |
| BARI MJI, % | 34.0 (25.5–38.0) | 30.0 (20.0–37.0) | 36.0 (30.0–38.0) | <0.001 |
| BARI MJI >35%, n (%) | 88 (47.6) | 24 (29.3) | 64 (62.1) | <0.001 |
| BARI MJI 18–35%, n (%) | 94 (50.8) | 56 (68.3) | 38 (36.9) | <0.001 |
| BARI MJI <18%, n (%) | 3 (1.6) | 2 (2.4) | 1 (1.0) | 0.585 |
| DILEMMA score | 5 (3–7) | 4 (2–5) | 7 (4–12) | <0.001 |
| DILEMMA score ≥9, n (%) | 42 (22.7) | 5 (6.1) | 37 (35.9) | <0.001 |
| DILEMMA score 3–8, n (%) | 107 (57.8) | 44 (53.7) | 63 (61.2) | 0.304 |
| DILEMMA score ≤2, n (%) | 36 (19.5) | 33 (40.2) | 3 (2.9) | <0.001 |
| Pressure analyses | ||||
| Resting Pd/Pa | 0.90 (0.87–0.94) | 0.93 (0.91–0.95) | 0.87 (0.85–0.90) | <0.001 |
BARI - bypass angioplasty revascularization investigation; FFR - fractional flow reserve; LAD - left anterior descending artery; LCX - left circumflex artery; LL - lesion length; MJI - myocardial jeopardy index; MLD - minimal lumen diameter; OM - obtuse marginal artery; PDA - posterior descending artery; Pd/Pa - distal coronary artery pressure/aortic pressure; QCA - quantitative coronary angiography; RCA - right coronary artery. Results were expressed as mean±standard deviation or median (interquartile range, 25th-75th percentile) in presence of abnormal distribution, and categorical variables as percentages. Comparisons were made using chi-square test for categorical variables, independent samples t-test for normally distributed variables, and Mann-Whitney U test for continuous variables not normally distributed