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. 2017 Jun 12;10:150. doi: 10.1186/s13068-017-0827-8

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© The Author(s) 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Process overview for the biological production of acetone from syngas. The fresh CO-rich gas is mixed with recycled gas and introduced into the reactor at the flow rate R _in. The recycled gas leaves the condensation unit with high pressure and is passed through a turbine (T) to adjust the pressure and to generate electricity, while syngas requires compression (C). The bubble column reactor has a height of 30 m and a diameter of 6 m. CO entering the liquid phase is assumed to be completely converted to acetone by the production strain Moorella thermoacetica. Acetone leaves the reactor with the off-gas; acetone and evaporated water are condensed and then separated in a distillation step. The water from the product recovery is recycled in the reactor