Table 5.
Backward Multivariable Cox Proportional Hazard Model for Predicting Stroke After LAA Closure
| Covariates | Unmatched Cohort | Propensity-Matched Cohort | ||
|---|---|---|---|---|
| OR (95% CI) | P Value | OR (95% CI) | P Value | |
| LAA closure | 1.02 (0.78–1.34) | 0.89 | 1.07 (0.72–1.58) | 0.74 |
| Age | 1.01 (1.01–1.02) | <0.001 | ||
| Prior stroke | 3.19 (2.73–3.71) | <0.001 | 3.77 (2.28–6.23) | <0.001 |
| Previous MI | 1.17 (1.03–1.32) | 0.02 | ||
| Peripheral arterial disease | 1.33 (1.15–1.54) | <0.001 | ||
| Calcium channel blocker | 1.18 (1.04–1.34) | 0.01 | ||
| ACE-I or ARB | 1.16 (1.03–1.30) | 0.01 | ||
| C-Statistic | 0.62 | 0.58 | ||
ACE-I Indicates angiotensin-converting enzyme inhibitor AFB, angiotensin receptor blocker; CI, confidence interval; LAA, left atrial appendage; MI, myocardial infraction; and OR, odds ratio.