A probabilistic hypercube. This can be interpreted as a geometrical representation of the output of a seat of classifiers, each one estimated with different types of data. The set of AD-PS scores corresponding to a given individual define a position inside the hypercube. The position of three individuals is illustrated. From Casanova et al [411]. Abbreviations: ADNI, Alzheimer’s Disease Neuroimaging Initiative; AD, Alzheimer’s Disease; CN, cognitively normal; GM, gray matter; WM, white matter.