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. 2017 Jun 7;37(23):5758–5769. doi: 10.1523/JNEUROSCI.0622-17.2017

Figure 3.

Figure 3.

A, Depiction of the three classifications of dendritic spines assessed in this study. BE, Representative dendrite segments from Tat (B) and Tat+ (D) D1 MSNs and from Tat (C) and Tat+ (E) D2 MSNs showing various dendritic spine morphologies. Scale bar, 3 μm. F, G, Percentage of morphologic spine types on D1 MSN dendrites was unchanged between Tat+ and Tat animals (F), whereas the percentage of filopodia/thin-shaped spines on D2 MSN dendrites was decreased in Tat+ animals (*p < 0.05), the percentage of stubby spines increased (**p < 0.05), and the proportion of mushroom-shaped spines was unchanged compared with Tat controls (G).