TABLE 1.
EC50 and maximal inhibition values for exogenous glycan inhibitors of spore adherence
Glycana | EC50 (μg/ml) | 95% Confidence intervals (μg/ml)
|
Maximal inhibition (% of control) | Mean estimated peak reductionb (μg/ml) ± SE | |
---|---|---|---|---|---|
Lower | Upper | ||||
Heparin | 0.097 | 0.059 | 0.157 | 73 | 28.4 ± 1.38 |
CSA | 14.08 | 6.44 | 30.78 | 83 | 18.0 ± 2.72 |
CSB | 0.641 | 0.193 | 2.13 | 88 | 11.2 ± 2.99 |
Mucin | 0.119 | 0.003 | 4.87 | 87 | 1.5 ± 3.33 |
Dextran sulfate | 53.67 | 19.45 | 414.11 | 81 | 15.3 ± 4.46 |
Dextran | No response curve | ||||
Hyaluronic acid | No response curve |
CSA, chondroitin sulfate A; CSB, chondroitin sulfate B.
Peak reduction is the lowest concentration of inhibitor calculated from standard curves to achieve maximal inhibition.