Figure 4.

Analogy of oversized allograft at lung transplantation to chest wall strapping (CWS). (A) Schematic flow–volume loops according to donor predicted values (black line) and measured mean values of recipients of oversized allografts (red line) during the early post-transplant period (1–6 mo). Flows are plotted against absolute lung volume. Adapted by permission from Reference 37. (B) Kaplan-Meier estimates of proportion of patients with bronchiolitis obliterans syndrome (BOS) stratified by recipients of undersized or oversized donor lungs. Oversized was defined as a donor-to-recipient predicted total lung capacity (pTLC) ratio greater than 1.0, and undersized was defined as a pTLC ratio of 1.0 or less. Comparison between over- and undersized cohorts was via log-rank test. Adapted by permission from Reference 37.