Table 3.
Comparison of respiratory effects of chest wall strapping, obesity, and transplantation of oversized lungs
Obesity (22) |
|||||
---|---|---|---|---|---|
Lung Function | CWS (1–10) | Mild, BMI 30–35 | Moderate, BMI 35–40 | Morbid, BMI >40 | Oversized Transplant (36) |
Lung Volumes | |||||
TLC, % predicted (SD) | 66% (5) | 93% (9) | 92% (11) | 88% (11) | 65% (13) |
FRC, % predicted (SD) | 70% (6) | 78% (13) | 72% (13) | 66% (12) | 81% (22) |
ERV, % predicted (SD) | 50% (9) | 42% (29) | 29% (19) | 24% (19) | 55% (18) |
Expiratory airflow | ↑↑ | ↑ (33, 34) | ↑ (33, 34) | variable | ↑↑ |
Slope of expiratory flow–volume loop | ↑↑ | ↑ (34) | ↑ (34) | variable | ↑↑ (37) |
Lung elastic recoil | ↑↑ | ↑ (24, 27, 28) | ↑↑ (24, 27, 28) | ↑↑ (24, 27, 28) | ↑ (38) |
Definition of abbreviations: BMI = body mass index; CWS = chest wall strapping; ERV = expiratory reserve volume; FRC = functional residual capacity; TLC = total lung capacity.
Supporting references are shown in parentheses, except SD where indicated.