Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Bile acid synthesis. Bile acid synthesis and biotransformation in this LiverChip model may primarily stem from cholesterol metabolism by CYP7A1. Cholic, glycocholic, taurocholic, and glycochinodeoxycholic acids were detected by ultra-HPLC-MS in the medium. A glycine-conjugated bile acid (e.g., GCA) was the most abundant bile acid identified and was characterized as a biomarker in this coculture system. Each well was sampled twice to evaluate technical variation. BA, bile acid.
