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. Author manuscript; available in PMC: 2017 Jun 13.
Published in final edited form as: Circ Heart Fail. 2012 Nov 20;6(1):118–126. doi: 10.1161/CIRCHEARTFAILURE.112.969576

Figure 4. TAC - Biochemical Data.

Figure 4

A. LV NADPH was increased by TAC in G6PDX mice. B. Superoxide production was decreased by G6PD deficiency. C. GSH was decreased in response to TAC in G6PDX mice. D. Lipid peroxidation products were unaffected by G6PD deficiency or TAC. E-G. TAC decreased myocardial aconitase activity, citrate synthase activity, and MCAD activity to the same extent in G6PDX and WT mice H-I. TAC increased ANP and MHCβ/MHCα in WT and G6PDX mice to the same extent. Data were obtained using LV myocardium from mice at 6 weeks after Sham or TAC surgery with a 28 gauge needle. *P <0.05 vs. Sham; #P <0.05 vs. WT; Sham n=7/group, TAC=10-12/group.