Table 1. Association Constants (Kobs) and Effective Molarities (EM) Measured by NMR Titrations and Dilutions in Toluene-d8 at 298 Ka.
| complex | Kobs (M–1) | Kfold | EMf (mM) | EMd (mM) | χfoldb |
|---|---|---|---|---|---|
| C8-PO | |||||
| A·D | 350 (3) | ||||
| AA·DD | 1900 (470) | 8 (3) | |||
| AD·ADc | 45 (15) | 2.2 (0.5) | 7 (1) | 0.69 (0.06) | |
| C8-N | |||||
| A·D | 34 (1) | ||||
| AA·DD | 130 (16) | 57 (8) | |||
| AD·AD | 60 (20) | n.d. | n.d. | 0 | |
| C8-NO | |||||
| A·D | 330 (80) | ||||
| AA·DD | 5400 (1600) | 30 (10) | |||
| AD·AD | 2400 (500) | n.d. | n.d. | 0 | |
| N8-PO | |||||
| A·D | 250 (10) | ||||
| AA·DD | 2500 (200) | 20 (2) | |||
| AD·AD | 225 (13) | 0.7 (0.1) | 3 (1) | 0.40 (0.03) | |
| N7-PO | |||||
| A·D | 250 (10) | ||||
| AA·DD | 1200 (400) | 10 (3) | |||
| AD·AD | 14 (5) | 3.6 (0.9) | 15 (4) | 0.78 (0.05) | |
| C9-PO | |||||
| A·D | 560 (210) | ||||
| AA·DD | 9000 (4000) | 14 (12) | |||
| AD·AD | 85 (22) | 4.1 (1.1) | 7 (3) | 0.81 (0.05) | |
| C7-POd | |||||
| A·D | 30 (1) | ||||
| AA·DD | 240 (80) | 130 (40) | |||
| AD·ADe | 130 (30) | n.d. | n.d. | 0 | |
a
Average values with errors (reported in parentheses) at the 95% confidence limit based on the variation between different signals and experiments.
c
AD 2-mer 16.
d
Experiments carried out in CDCl3 due to the high stability of the complexes in toluene-d8.
e
AD 2-mer 44. n.d. = not detected.