Figure 3. Lcn2 expressing L. lactis (Lactis^Lcn2) exhibits augmented resistance to various stressors.

Equal amount of Lactis^Lcn2 or Lactis^Con (1 x 10⁶ CFU) were cultured at the indicated (A) pH, or in the presence of (B) taurocholate, (C) glycocholate, (D) lithocholic acid and (E) deoxycholic acid at the indicated concentration. Lactis^Lcn2 or Lactis^Con were subjected to the indicated concentration of (F) H₂O₂, (G) H₂O₂ with aeration, and (H) myeloperoxidase (MPO)-mediated bacterial killing. All experiments were performed in triplicates and are representative of three independent experiments. Results are expressed as mean ± SEM. *p < 0.05.