Table 2.

Sputum-smear and culture conversion time in per protocol group i.e. patients who completed the treatment.

Week	Smear conversion till (in weeks)				P	Odds Ratio (95% C.I.)	Culture conversion till (in weeks)				P	Odds Ratio (95% C.I.)
	MIP Arm (N = 328)		Placebo Arm(N = 314)				MIP Arm (N = 328)		Placebo Arm (N = 314)
	Converted (Cumulative numbers)	%	Converted (Cumulative numbers)	%			Converted (Cumulative numbers)	%	Converted (Cumulative numbers)	%
2	175	53.35	153	48.7	0.24	1.2 (0.87–1.66)	139	42.37	118	37.5	0.215	1.22 (0.87–1.69)
4	234	71.34	216	68.78	0.48	1.13 (0.79–1.61)	220	67.1	179	57.0	0.0002*	1.86 (1.31–2.64)
6	268	81.7	242	77.1	0.146	1.33 (0.89–1.98)	257	78.35	215	68.47	0.0046*	1.67 (1.15–2.41)
8	281	85.67	261	83.1	0.37	1.21 (0.77–1.9)	286	87.1	248	78.98	0.0054*	1.8 (1.16–2.84)
12	298	90.85	274	87.3	0.14	1.45 (0.85–2.48)	301	91.77	269	85.67	0.014*	1.86 (1.1–3.22)
16	303	92.37	280	89.17	0.16	1.47 (0.82–2.64)	303	92.37	270	85.98	0.009*	1.97 (1.14–3.46)
26	305	92.98	283	90.13	0.19	1.45 (0.79–2.67)	306	93.29	275	87.58	0.0136*	1.97 (1.1–3.58)
35	306	93.29	283	90.13	0.15	1.52 (0.83–2.83)	306	93.29	277	88.2	0.026**	1.86 (1.03–3.39)
36	—	—	—	—			309	94.2	280	89.17	0.02*	1.97 (1.06–3.75)
39	309	94.2	284	90.4	0.073	1.72 (0.91–3.3)	309	94.2	280	89.17	0.02*	1.97 (1.06–3.75)
40	—	—	—	—			—		281	89.49
Median Time (range)	2 (2–39)		2 (2–39)				4 (2–36)		4 (2–40)

*P value significant after Boneferroni’s correction. **Corrected p value not significant.