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. 2017 Jun 13;7:3357. doi: 10.1038/s41598-017-03445-x

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Exported protein families in Babesia canis. (A) In silico predicted exported protein families. Bar colours indicate the predicted route of secretion and/or type of membrane anchoring. cSP: canonical signal peptide; aSP: alternative (non-classical) secretory pathway; TM: transmembrane domain; GPI: predicted glycophosphatidylinositol anchor. (B) Transcript abundances of exported proteins. Each dot corresponds to the transcript abundance (FPKM) for each gene in the family during acute crisis in a splenectomised dog. Red bars indicate the median FPKM values in the presented protein family. FPKM: Fragments Per Kilobase of exon model per Million mapped reads.