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. 2017 Jun 13;7:3385. doi: 10.1038/s41598-017-03457-7

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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The muPA:Nb22 complex crystal structure. (a) Cartoon representation of the overall crystal structure of the serine protease domain of muPA (orange) in complex with Nb22 (pink). (b) Displays the active site region of muPA in the muPA:Nb22 complex. Arg104 and Asp105 of Nb22 (pink) and Ile16, His57, Asp189, Asp194 and Ser195 of muPA (orange) is shown as sticks.