Table 2.
Chrysophsin-1 (Chr-1) and its designed novel analogs with glycine residue(s) of GXXXXG motifs substituted with proline residue(s).
| S.No | Peptide | Sequence | Charge (Znet) | Calculated M.W. | Observed M.W. | % Hydrophobicity |
|---|---|---|---|---|---|---|
| 1 | Chr-1 | GXXXXGXXXXGXXXXGFFGWLIKGAIHAGKAIHGLIHRRRH | +5 | 2892.79 | 2892.81 | 48% |
| 2 | G8P-Chr-1 | FFGWLIKPAIHAGKAIHGLIHRRRH | +5 | 2932.85 | 2932.88 | 48% |
| 3 | G13P-Chr-1 | FFGWLIKGAIHAPKAIHGLIHRRRH | +5 | 2932.85 | 2932.86 | 48% |
| 4 | G18P-Chr-1 | FFGWLIKGAIHAGKAIHPLIHRRRH | +5 | 2932.85 | 2932.86 | 48% |
| 5 | G13,18P-Chr-1 | FFGWLIKGAIHAPKAIHPLIHRRRH | +5 | 2972.91 | 2972.94 | 48% |
Glycine residues of GXXXXG motifs are marked as bold and underlined letters whereas proline residues are marked in bold, underlined and italics.