Table. 1.
Hematological and biochemical profile of acute and sub-acute toxicity studies on swiss albino mice treated with BGT.
| Biochemical and haematological Parameters | Acute Toxicity | Sub-acute toxicity | ||
|---|---|---|---|---|
| Control | 5000 mg/kg of body weight | Control | 5000 mg/kg of body weight | |
| Sugar (mg/dL) | 101.25 ± 2.59 | 103.25 ± 3.01 | 110.5 ± 2.33 | 113.2 ± 5.79 |
| HB (gm %) | 14.20 ± 1.20 | 13.13 ± 0.52 | 14.10 ± 0.72 | 13.63 ± 1.04 |
| WBC (103/mm3) | 6.8 ± 0.14 | 7.2 ± 0.43 | 8.3 ± 481.32 | 8.5 ± 355.90 |
| RBC (106/mm3) | 4.75 ± 0.41 | 4.48 ± 0.27 | 4.68 ± 0.23 | 4.53 ± 0.33 |
| SGOT (U/L) | 67.50 ± 6.81 | 67.0 ± 1.83 | 41.75 ± 4.27 | 62.25 ± 17.31 |
| SGPT (U/L) | 44.50 ± 2.33 | 43.00 ± 3.54 | 24.75 ± 6.34 | 34.00 ± 18.76 |
| ALP (U/L) | 99.25 ± 5.28 | 102.75 ± 1.44 | 98.25 ± 9.29 | 119.75 ± 24.50 |
| Urea (mg %) | 37.25 ± 1.55 | 38.50 ± 1.04 | 32.38 ± 10.58 | 65.40 ± 3.69 |
| Creatinine (mg %) | 0.28 ± 0.09 | 0.4 ± 0.09 | 0.30 ± 0.04 | 0.45 ± 0.10 |
| Protein (g %) | 13.08 ± 0.65 | 13.63 ± 1.04 | 4.05 ± 0.33 | 4.93 ± 0.18 |
| Albumin | 7.68 ± 0.40 | 8.10 ± 0.51 | 2.73 ± 0.28 | 3.33 ± 0.20 |
| Cholesterol (mg/dL) | 135.25 ± 11.6 | 135.25 ± 5.57 | 47.00 ± 3.56 | 22.25 ± 19.95 |
| TGL (mg/dL) | 73.25 ± 5.63 | 77.00 ± 5.21 | 39.50 ± 1.26 | 42.00 ± 4.02 |
| HDL (mg/dL) | 21.50 ± 2.10 | 19.75 ± 1.11 | 9.00 ± 1.08 | 7.50 ± 0.96 |
| LDL (mg/dL) | 86.70 ± 7.65 | 84.18 ± 6.53 | 28.25 ± 4.08 | 43.30 ± 7.52 |
| VLDL (mg/dL) | 27.05 ± 2.33 | 27.05 ± 1.11 | 7.75 ± 0.34 | 8.40 ± 0.80 |
The results are expressed as mean ± SD.