. 2005 Feb;73(2):972–980. doi: 10.1128/IAI.73.2.972-980.2005

TABLE 3.

V. cholerae gene products identified by RIVET as being transcriptionally induced during infection of the infant mouse small intestine compared to during growth in LB broth

Gene product^a:	Cassette^b	Allele^c	% of CFU resolved		Ratio^f	No. of mice^g	P value^h
Gene product^a:	Cassette^b	Allele^c	In vitro^d	In vivo^e	Ratio^f	No. of mice^g	P value^h
VCA1008	res	tnpR^mut135	<0.1	77	770	4	<0.05
VC2487	res1	tnpR^mut168	<0.1	72	720	4	<0.05
VC2641	res1	tnpR^mut135	<0.1	70	700	4	<0.05
VC0488	res	tnpR^mut168	<0.1	22	221	4	<0.05
VC0063	res1	tnpR^mut135	0.1	22	220	4	<0.05
VCA1057	res	tnpR^mut135	0.3	35	117	4	<0.05
VCA0773	res1	tnpR^mut168	1	100	100	7	<0.05
VC0622	res1	tnpR^mut168	0.1	10	100	4	<0.05
VC1111	res	tnpR^mut135	<1	87	87	6	<0.05
VC0207	res	tnpR^mut168	<0.1	8	80	8	0.2
VC0721	res1	tnpR^mut135	<0.1	4	40	4	<0.05
VC1658	res	tnpR^mut168	3	88	30	4	<0.05
VC2373	res1	tnpR^mut168	0.1	3	30	4	0.1
VC0201	res1	tnpR^mut135	0.6	17	28	4	<0.05
VCA0529	res	tnpR	0.2	2	20	4	<0.05
VC0874	res1	tnpR	<1	19	19	5	<0.05
VC1173	res	tnpR^mut168	1	16	16	4	0.2
VC0202	res1	tnpR	7	94	13	3	<0.05
VC0203	res1	tnpR^mut168	2	25	13	7	<0.05
VC1137	res	tnpR^mut135	<1	12	12	8	<0.05
VC1535	res	tnpR	8	93	12	19	<0.05
VC1275	res	tnpR	8	85	11	4	<0.05
VC0130	res1	tnpR^mut168	0.2	2	10	4	0.1
VC1338	res1	tnpR	3	30	10	4	0.05
VC2621	res	tnpR^mut168	12	90	7.5	4	<0.05
VCA0632	res1	tnpR	11	77	7	3	<0.05
VC2419	res	tnpR^mut135	5	34	6.8	4	<0.05
VC1500	res	tnpR	10	66	6.6	4	<0.05
VCA0752	res	tnpR^mut168	4	24	6	7	<0.05
VCA0687	res	tnpR^mut168	0.2	1	5	4	0.05
VC2705	res	tnpR	3	12	4	4	<0.05
VC1687	res	tnpR^mut135	5	18	3.6	4	0.07
VC2742	res1	tnpR^mut168	1.4	5	3.6	4	<0.05
VCA0016	res1	tnpR^mut168	7	24	3.4	4	<0.05
VCA0242	res1	tnpR	2.5	8.4	3.4	4	0.1
VC2646	res1	tnpR^mut135	8	18	2.2	3	0.07
VC2130	res1	tnpR^mut168	35	76	2.2	4	<0.05
VC1619.1	res	tnpR^mut168	13	25	1.9	8	<0.05
VCA0014	res	tnpR^mut168	12	18	1.5	4	0.1
VC1034	res1	tnpR	75	100	1.3	4	<0.05

Gene product designation by the Institute for Genomic Research.

res or res1 cassette in GOA1245 or GOA1246 strain background, respectively.

Wild-type, mut168, or mut135 RBS mutant allele of tnpR gene fused to V. cholerae gene.

Percent resolved CFU determined after 11 generations in LB broth.

Percent resolved CFU determined after 24 h of infection in the infant mouse small intestine.

The ivi genes were ranked by their ratio of percent resolution in vivo/in vitro.

Number of mice used per experiment to determine percent resolution in vivo.

Calculated by Student's two-tailed t test between the percent resolution values obtained in vivo and in vitro.