Figure 1.

The establishment, extinction and reestablishment of odorant-induced whisker motion in mice. (A) Presents whisker motions in response to the odor-test (black traces on top) in conditioned reflex (CR)-formation mice and unpaired stimulus (UPS) mice at the days 1, 10, 17 and 18. The paired or unpaired trainings were given from day 1 to day 10 as well as at day 18, however, the non-training was between day 11 and 16. Calibration bars are 30° and 5 s. (B) illustrates the angles of whisker fluctuation in response to the odor-test during different training days in CR-formation mice (round symbols) and UPS mice (triangles), indicating odorant-induced whisker motion in terms of establishment, decay and reestablishment. (C) illustrates the comparisons of whisking angles in response to the odor-test in CR-formation mice (filled bars) and UPG mice (hollow bars) at training days 1, 10, 17 and 18. (D) shows the comparisons of whisking frequencies in response to the odor-test in CR-formation mice (filled bars) and UPG mice (hollow bars) at training days 1, 10, 17 and 18. (E) illustrates the comparisons of whisker retraction duration in response to the odor-test in CR-formation mice (filled bars) and UPG mice (hollow bars) at the training days 1, 10, 17 and 18. Two asterisks show p < 0.01 (Statistical significance was determined using two-way analysis of variance (ANOVA) with a Bonferroni correction for multiple comparisons).