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PEE modifies NMDAR mRNA expression in rat brains. Total RNA was obtained from the Prefrontal cortex, (PFC), Hippocampus (HIPP), and Ventral tegmental area (VTA) from Control or PEE rats of 21 (P21) (A) or 70 (P70) (B) days old. RT-qPCR was performed using specific primers for NMDAR mRNA subunits (NR1 and NR2B). Data is expressed as a fold of expression in PEE vs. control samples. N = 3–5 litters. *P < 0.05, **P < 0.01 (paired Student's t-test compared with 1).
