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Brain endophenotype of obesity vulnerability. Personality, cognitive, and functional brain imaging characteristics that increase obesity vulnerability. Uncontrolled eating (UE) results from an interaction of elevated reward sensitivity and poor self-control. OFC, orbitofrontal cortex; PFC, prefrontal cortex; ACC, anterior cingulate cortex; BED, binge-eating disorder; ADHD, attention deficit/hyperactivity disorder; BMI, body mass index.
