Figure 1.

Sample simulated output from four different models of effect of mass drug administration on all-age PCR prevalence of Plasmodium falciparum infection

From year −1 to year 0, the models are at equilibrium. The timing of each round of mass drug administration in each model is shown by coloured arrows. The four different models show the output under the standard intervention scenario (70% coverage, 2 years of mass drug administration, two rounds per year, 5 weeks between rounds, seasonal transmission [based on Zambia], and 5% mean annual prevalence pre-intervention by microscopy in 2–10-year-olds). DTK=Disease Transmission Kernel. MORU=Mahidol Oxford Tropical Medicine Research Unit.