Table 1.
Demographic and Clinicopathologic characteristics of the three studied groups.
| Parameter | Healthy controls (n = 60) | CHC (n = 60) | HCC (n = 60) | P |
|---|---|---|---|---|
| Age | 33.9 ± 8.64a | 35.1 ± 6.7a | 52.3 ± 10.7 | 0.002 |
| Gender m/f (%) | 36/24 (60/40) | 41/19 (68.3/31.7) | 42/18 (70/30) | 0.106 |
| Albumin (g/dl) | 4.11 ± 0.89a | 3.61 ± 1.42a | 2.91 ± 1.11 | 0.003 |
| INR | 1.11 ± 0.027a | 1.41 ± 0.64b | 1.22 ± 0.49a | 0.011 |
| T. bilirubin (mg/dl) | 1.1 ± 0.28a | 2.07 ± 1.33b | 2.74 ± 1.06b | 0.003 |
| AST (IU/ml) | 20.9 ± 7.89a | 56.22 ± 11.33b | 107.58 ± 19.3c | 0.001 |
| ALT (IU/ml) | 26.1 ± 7.9a | 62.11 ± 20.13b | 97.65 ± 20.11c | 0.001 |
| Platelets (103/μl) | 215.11 ± 60.13a | 140.22 ± 42.1b | 120.11 ± 44.1c | 0.001 |
| AAR | 26.11 ± 4.79a | 62.7 ± 15.11b | 81.1 ± 16.33c | 0.011 |
| APRI | 31.2 ± 7.98a | 61.1 ± 18.7b | 80.1 ± 13.33c | 0.021 |
| α-Fetoprotein (ng/ml) | 3.88 ± 1.71a | 46.25 ± 28.11b | 217.33 ± 136c | 0.022 |
| T.C (mg/dl) | 192.11 ± 19.36a | 168.11 ± 13.2b | 160.01 ± 21.3b | 0.001 |
| LDL-C (mg/dl) | 119.12 ± 10.21a | 93.68 ± 7.11b | 90.65 ± 18.11b | 0.003 |
| HDL-C (mg/dl) | 49.11 ± 4.82 | 47.33 ± 4.78 | 46.12 ± 9.25 | 0.092 |
| TG (mg/dl) | 175.33 ± 10.31a | 115.13 ± 11.6b | 112.75 ± 22.1b | 0.001 |
Values are expressed as means ± SE; mean values within a row not sharing a common superscript letter (a, b, c) were significantly different; P < 0.05.