Table 2.
Metabolic lactate production of various LDL exposure to macrophages. Mean peak MAMP height changes and standard errors for each experimental condition during exposure. All p values are calculated based on peak height versus 10 min average basal value prior to exposure. Terms in bold are representative of p < 0.05, indicating statistical significance.
| Lactate | |||||
|---|---|---|---|---|---|
| Native LDL (%) | Low oxLDL (%) | Medium oxLDL (%) | High oxLDL (%) | Intracel oxLDL (%) | |
| 1 µg/ml | 3.2 ± 0.68 | 1.42 ± 1.58 | 1.81 ± 1.3 | 1.54 ± 2.8 | 2.0 ± 2.1 |
| p = 0.0022 | p = 0.3987 | p = 0.2047 | p = 0.6001 | p = 0.3875 | |
| 10 µg/ml | 1.0 ± 1.0 | 0.39 ± 1.5 | 17.2 ± 20.0 | 0.91 ± 0.63 | 2.7 ± 0.66 |
| p = 0.3699 | p = 0.8039 | p = 0.4134 | p = 0.2198 | p = 0.0143 | |
| 50 µg/ml | 0.47 ± 1.1 | 0.84 ± 0.16 | 0.38 ± 3.8 | 2.0 ± 1.8 | 8.1 ± 2.35 |
| p = 0.698 | p = 0.0040 | p = 0.9534 | p = 0.3012 | p = 0.0117 | |
| 100 µg/ml | 4.0 ± 1.5 | 2.7 ± 1.1 | 1.21 ± 1.2 | 15.2 ± 4.29 | 7.03 ± 3.0 |
| p = 0.0445 | p = 0.0441 | p = 0.379 | p = 0.0172 | p = 0.0438 | |