Table 3.
Metabolic oxygen consumption of various LDL exposure to macrophages. Mean peak MAMP height changes and standard errors for each experimental condition during exposure. All p values are calculated based on peak height versus 10 min average basal value prior to exposure. Terms in bold are representative of p < 0.05, indicating statistical significance.
Oxygen | |||||
---|---|---|---|---|---|
Native LDL (%) | Low oxLDL (%) | Medium oxLDL (%) | High oxLDL (%) | Intracel oxLDL (%) | |
1 µg/ml | 2.9 ± 0.36 | 11.8 ± 6.3 | 0.39 ± 0.72 | 21.7 ± 20.3 | 1.6 ± 4.2 |
p = 0.0013 | p = 0.1053 | p = 0.6596 | p = 0.3639 | p = 0.7151 | |
10 µg/ml | 0.3 ± 1.2 | 3.47 ± 5.9 | 17.1 ± 14.1 | 6.27 ± 6.55 | 1.0 ± 1.65 |
p = 0.8103 | p = 0.8338 | p = 0.2794 | p = 0.3822 | p = 0.5915 | |
50 µg/ml | 1.3 ± 2.2 | 12.8 ± 11.2 | 22.6 ± 20.7 | 2.8 ± 0.78 | 8.88 ± 1.47 |
p = 0.583 | p = 0.3748 | p = 0.3114 | p = 0.0161 | p = 0.0028 | |
100 µg/ml | 1.7 ± 0.6 | 12.1 ± 15.9 | 20.7 ± 18.2 | 2.36 ± 1.21 | 3.14 ± 1.7 |
p = 0.0371 | p = 0.5028 | p = 0.3084 | p = 0.1594 | p = 0.1085 |