Table 1.
Patient characteristics and hormonal test data.
| Case # | age (year) | sex | hight | weight | BMI (kg/m2) | screening test for PA
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confirmatory tests for PA
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adrenal venous sampling data
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|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PAC | PRA | ARR | SIT (PAC after infusion) | captopril challenge test | FUT (PRA after loading) | right adrenal vein data | left adrenal vein data | peripheral vein data | lateralization data | |||||||||||||||||
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| PAC pre | PAC post | PRA post | ARR post | % decrease of PAC | PAC | PCC | ACR | PAC | PCC | ACR | PAC | PCC | ACR | LR | CR | |||||||||||
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| normal range/cut off | <25 | 39–159 | 0.3–2.9 | <200 | <50*/<60** | <200* | >30** | <1* | >4*/>2.6** | <1 | ||||||||||||||||
| 1 | 64 | M | 167.8 | 61.7 | 21.9 | 214 | 0.4 | 535.0 | NA | 132 | 97 | 0.2 | 485 | 26.5 | 0.9 | 6514 | 529.8 | 12.3 | 32,180 | 511 | 63.0 | 199 | 17.4 | 11.4 | 5.12 | 1.08 |
| 2 | 61 | M | 169.2 | 56.0 | 19.6 | 198 | 0.3 | 660.0 | NA | 158 | 94.8 | 0.5 | 189.6 | 40.0 | 1.4 | 9100 | 1115 | 8.2 | 72,800 | 1188 | 61.3 | 225 | 19.3 | 11.6 | 7.51 | 0.70 |
| 3 | 35 | F | 152.4 | 49.8 | 21.4 | 229 | 0.4 | 572.5 | 336 | 310 | 283 | 1 | 283 | 8.7 | 0.8 | 19,800 | 822 | 24.1 | 53,300 | 446 | 119.5 | 700 | 24.3 | 28.8 | 4.96 | 0.84 |
| 4 | 37 | M | 162.0 | 62.2 | 23.7 | 233 | 0.7 | 332.9 | 80 | 130 | 125 | 0.4 | 312.5 | 3.8 | 1.3 | 7420 | 1160 | 6.4 | 39,500 | 988 | 40.0 | 320 | 27.5 | 11.6 | 6.25 | 0.55 |
BMI: body mass index (normal range: <25), M: male, F: female, PAC: plasma aldosterone concentration (pg/mL), PRA: plasma renin activity (ng/ml/h),
*
criteria in US guideline of PA (Funder et al., 2008),
**
criteria in Japanese Guideline of PA (Nishikawa et al., 2011),
FUT: furosemide upright test, PCC: plasma cortisol concentration, ACR: aldosterone cortisol ratio (PAC/PCC), LR: lateralized ratio, CR: contralateral ratio, NA: not available, PA: primary aldosteronism, SIT: saline infusion test.