Table 1.
Clinical characteristics of healthy controls and HD patients.
| HD Patients | Healthy Controls | p-value | |
|---|---|---|---|
| No. of patients | 16 | 16 | |
| Age (years old) | 61.4 ± 10.5 | 62.1 ± 7.9 | 0.678 |
| HD duration (months) (range) | 30.2 (1-85) | - | - |
| HD time/day (hours) | 4.3 ± 0.6 | - | - |
| Body Mass Index (kg/m2) | 22.6 ± 3.5 | 25.5 ± 4.3 | 0.014 |
| Systolic blood pressure (mmHg) | 148 ± 25 | 139 ± 20 | 0.247 |
| Hemoglobin (g/dL) | 11.6 ± 1.1 | 14.6 ± 1.5 | <0.001 |
| Total protein (g/dL) | 6.21 ± 0.55 | 7.53 ± 0.45 | <0.001 |
| Albumin (g/dL) | 3.31 ± 0.44 | 4.56 ± 0.25 | <0.001 |
| AST (IU/L) | 19.6 ± 12.8 | 27.4 ± 10.2 | 0.065 |
| ALT (IU/L) | 15.3 ± 8.0 | 29.4 ± 18.5 | 0.009 |
| BUN (mg/dL) | 50.2 ± 12.1 | 18.6 ± 6.3 | <0.001 |
| Serum Cr (mg/dL) | 9.10 ± 3.34 | 0.81 ± 0.11 | <0.001 |
| Uric acid (mg/dL) | 6.86 ± 1.01 | 6.22 ± 1.35 | 0.203 |
| Corrected Ca (mg/dL) | 9.33 ± 0.43 | - | - |
| Phosphate (mg/dL) | 5.29 ± 1.36 | - | - |
| Total-cholesterol (mg/dL) | 159 ± 27 | 183 ± 38 | 0.057 |
| LDL-cholesterol (mg/dL) | 54 ± 22 | 109 ± 35 | 0.024 |
| Triglycerides (mg/dL) | 97 ± 46 | 99 ± 49 | 0.953 |
| Diabetes (No.) (-/+) | 8/8 | 16/0 | - |
| SDS | 43.8 ± 7.3 | - | - |
| Medication | |||
| RAS inhibitors (No.) (-/+) | 0/16 | 16/0 | - |
| Statins (No.) (-/+) | 8/8 | 16/0 | - |
Values are shown as mean±SD or range. No.=number. HD=hemodialysis; AST=aspartate aminotransaminase; ALT=alanine aminotransaminase; BUN=blood urea nitrogen; Cr=creatinine; Ca=calcium; LDL=low-density lipoprotein; SDS=self-rating depression scale; RAS=renin-angiotensin system.