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. 2017 May 18;8(6):1573–1586. doi: 10.1016/j.stemcr.2017.04.019

Table 1.

Biological and Cytogenetic-Molecular Characteristics of Blasts and BM-MSCs from Diagnostic AML Patients

Patient ID Diagnostic Cytogenetics Molecular Age (years) Gender Blasts (%) Risk Cytogenetic/Molecular Alteration in BM-MSCs
AML01 AML-M4 46, XY, inv(16) Cbfb-MYH11 20 M 56 low negative
AML02 AML-M5 46, XY, inv(16) Cbfb-MYH11 1 M 50 low negative
AML03 AML-M2 46, XY, t(8;21) AML1-ETO 30 M 39 low ND
AML04 AML 46, XX NPM1MUT, IDH1MUT 20 F 92 low negative
AML05 AML 46, XY NPM1MUT 18 M 32 low negative
AML06 AML 46, XY, t(5;15) cEBPaMUT 66 M 15 low negative
AML07 AML-M4 46, XX NPM1MUT 37 F 80 low negative
AML08 AML-M3 46, XX t(15;17) PML-RARa 59 F 90 low negative
AML09 AML-5b 46, XX NPM1MUT 70 F 34 low ND
AML10 AML-M3 46, XY, t(15;17) PML-RARa 27 M 92 low negative
AML11 AML 46, XY NPM1MUT 81 M 45 low ND
AML12 AML 46, XY NPM1MUT 80 M 49 low negative
AML13 AML 46, XX NPM1MUT 71 F 45 low ND
AML14 AML 46, XX NPM1MUT 78 F 67 low negative
AML15 AML-M3 46, XY, t(15;17) PML-RARa 25 M 90 low negative
AML16 AML-M3 46, XY, inv(16) Cbfb-MYH11 27 M 40 low negative
AML17 AML 46, XY 10 M 92 int ND
AML18 AML 46, XY 81 M 35 int ND
AML19 AML 46, XY 77 M 45 int ND
AML20 AML 46, XX 61 F 71 int ND
AML21 AML-M4 46, XY 86 M 50 int ND
AML22 AML 46, XX 52 F 79 int ND
AML23 AML 46, XY 78 M 60 int ND
AML24 AML-M4 46, XX 44 F 65 int ND
AML25 AML 46, XY 61 M 1 int ND
AML26 AML-M7 46, XY 60 M 60 int ND
AML27 AML 46, XY 56 M 40 int ND
AML28 AML-M5 46, XX, t(11;19) MLL-ENL 48 F 77 high negative
AML29 AML 45, XY, −7 80 M 85 high negative
AML30 AML-M2 46, XX, t(8;21) AML1-ETO, FLT3-ITD 4 F 40 high negative/negative
AML31 AML-M4 46, XX, t(9;11) MLL-AF9 63 F 90 high negative
AML32 AML 45, XY, −7 73 M 15 high negative
AML33 AML-M5 46, XY NPM1MUT, FLT3del 77 M 80 high negative/negative
AML34 AML-M5 46, XX NPM1MUT, FLT3-ITD 65 F 90 high negative/negative
AML35 AML-M1 46, XX NPM1MUT, FLT3-ITD 73 F 90 high negative
AML36 AML 46, XX, 11q23 MLL-MLL (PTD) 74 F 70 high ND
AML37 AML-M1 46, XX, t(9;11) MLL-AF9 77 F 80 high negative
AML38 AML 45, XY, −7 69 M 22 high negative
AML39 AML-M4 46, XY NPM1MUT, FLT3MUT, WT1MUT 42 M 99 high negative
AML40 AML CK 35 M 80 high negative
AML41 AML 47, XY (+mar) FLT3 D835MUT 81 M 47 high negative
AML42 AML-M2 46, XX MLL-PTD+ 76 F 40 high negative
AML43 AML 46, XY, −7q 53 M 56 high negative
AML44 AML-M4 47, XY, +8 WT1+, TP53 exon 6+ 69 M 35 high ND
AML45 AML-M4 46, XX MLL-PTD+ 68 F 65 high negative
AML46 AML 46, XX FLT3-ITD 8 F 95 high negative
HD01 normal 46, XX 37 F 0 HD ND
HD02 normal 46, XY 34 M 0 HD ND
HD03 normal 46, XY 41 M 0 HD ND
HD04 normal 46, XY 42 M 0 HD ND
HD05 normal 46, XY 42 M 0 HD ND
HD06 normal 46, XX 34 F 0 HD ND
HD07 normal 46, XY 28 M 0 HD ND
HD08 normal 46, XX 49 F 0 HD ND
HD09 normal 46, XY 56 M 0 HD ND
HD10 normal 46, XX 34 F 0 HD ND

HD, healthy donor; CK, complex karyotype; int, intermediate risk; M, male; F, female; –, no mutations found for FLT3, NPM1, cEBPa, WT, and IDH1; ND, not determined.