Table 1.
Patient ID | Diagnostic | Cytogenetics | Molecular | Age (years) | Gender | Blasts (%) | Risk | Cytogenetic/Molecular Alteration in BM-MSCs |
---|---|---|---|---|---|---|---|---|
AML01 | AML-M4 | 46, XY, inv(16) | Cbfb-MYH11 | 20 | M | 56 | low | negative |
AML02 | AML-M5 | 46, XY, inv(16) | Cbfb-MYH11 | 1 | M | 50 | low | negative |
AML03 | AML-M2 | 46, XY, t(8;21) | AML1-ETO | 30 | M | 39 | low | ND |
AML04 | AML | 46, XX | NPM1MUT, IDH1MUT | 20 | F | 92 | low | negative |
AML05 | AML | 46, XY | NPM1MUT | 18 | M | 32 | low | negative |
AML06 | AML | 46, XY, t(5;15) | cEBPaMUT | 66 | M | 15 | low | negative |
AML07 | AML-M4 | 46, XX | NPM1MUT | 37 | F | 80 | low | negative |
AML08 | AML-M3 | 46, XX t(15;17) | PML-RARa | 59 | F | 90 | low | negative |
AML09 | AML-5b | 46, XX | NPM1MUT | 70 | F | 34 | low | ND |
AML10 | AML-M3 | 46, XY, t(15;17) | PML-RARa | 27 | M | 92 | low | negative |
AML11 | AML | 46, XY | NPM1MUT | 81 | M | 45 | low | ND |
AML12 | AML | 46, XY | NPM1MUT | 80 | M | 49 | low | negative |
AML13 | AML | 46, XX | NPM1MUT | 71 | F | 45 | low | ND |
AML14 | AML | 46, XX | NPM1MUT | 78 | F | 67 | low | negative |
AML15 | AML-M3 | 46, XY, t(15;17) | PML-RARa | 25 | M | 90 | low | negative |
AML16 | AML-M3 | 46, XY, inv(16) | Cbfb-MYH11 | 27 | M | 40 | low | negative |
AML17 | AML | 46, XY | – | 10 | M | 92 | int | ND |
AML18 | AML | 46, XY | – | 81 | M | 35 | int | ND |
AML19 | AML | 46, XY | – | 77 | M | 45 | int | ND |
AML20 | AML | 46, XX | – | 61 | F | 71 | int | ND |
AML21 | AML-M4 | 46, XY | – | 86 | M | 50 | int | ND |
AML22 | AML | 46, XX | – | 52 | F | 79 | int | ND |
AML23 | AML | 46, XY | – | 78 | M | 60 | int | ND |
AML24 | AML-M4 | 46, XX | – | 44 | F | 65 | int | ND |
AML25 | AML | 46, XY | – | 61 | M | 1 | int | ND |
AML26 | AML-M7 | 46, XY | – | 60 | M | 60 | int | ND |
AML27 | AML | 46, XY | – | 56 | M | 40 | int | ND |
AML28 | AML-M5 | 46, XX, t(11;19) | MLL-ENL | 48 | F | 77 | high | negative |
AML29 | AML | 45, XY, −7 | – | 80 | M | 85 | high | negative |
AML30 | AML-M2 | 46, XX, t(8;21) | AML1-ETO, FLT3-ITD | 4 | F | 40 | high | negative/negative |
AML31 | AML-M4 | 46, XX, t(9;11) | MLL-AF9 | 63 | F | 90 | high | negative |
AML32 | AML | 45, XY, −7 | – | 73 | M | 15 | high | negative |
AML33 | AML-M5 | 46, XY | NPM1MUT, FLT3del | 77 | M | 80 | high | negative/negative |
AML34 | AML-M5 | 46, XX | NPM1MUT, FLT3-ITD | 65 | F | 90 | high | negative/negative |
AML35 | AML-M1 | 46, XX | NPM1MUT, FLT3-ITD | 73 | F | 90 | high | negative |
AML36 | AML | 46, XX, 11q23 | MLL-MLL (PTD) | 74 | F | 70 | high | ND |
AML37 | AML-M1 | 46, XX, t(9;11) | MLL-AF9 | 77 | F | 80 | high | negative |
AML38 | AML | 45, XY, −7 | – | 69 | M | 22 | high | negative |
AML39 | AML-M4 | 46, XY | NPM1MUT, FLT3MUT, WT1MUT | 42 | M | 99 | high | negative |
AML40 | AML | CK | – | 35 | M | 80 | high | negative |
AML41 | AML | 47, XY (+mar) | FLT3 D835MUT | 81 | M | 47 | high | negative |
AML42 | AML-M2 | 46, XX | MLL-PTD+ | 76 | F | 40 | high | negative |
AML43 | AML | 46, XY, −7q | – | 53 | M | 56 | high | negative |
AML44 | AML-M4 | 47, XY, +8 | WT1+, TP53 exon 6+ | 69 | M | 35 | high | ND |
AML45 | AML-M4 | 46, XX | MLL-PTD+ | 68 | F | 65 | high | negative |
AML46 | AML | 46, XX | FLT3-ITD | 8 | F | 95 | high | negative |
HD01 | normal | 46, XX | – | 37 | F | 0 | HD | ND |
HD02 | normal | 46, XY | – | 34 | M | 0 | HD | ND |
HD03 | normal | 46, XY | – | 41 | M | 0 | HD | ND |
HD04 | normal | 46, XY | – | 42 | M | 0 | HD | ND |
HD05 | normal | 46, XY | – | 42 | M | 0 | HD | ND |
HD06 | normal | 46, XX | – | 34 | F | 0 | HD | ND |
HD07 | normal | 46, XY | – | 28 | M | 0 | HD | ND |
HD08 | normal | 46, XX | – | 49 | F | 0 | HD | ND |
HD09 | normal | 46, XY | – | 56 | M | 0 | HD | ND |
HD10 | normal | 46, XX | – | 34 | F | 0 | HD | ND |
HD, healthy donor; CK, complex karyotype; int, intermediate risk; M, male; F, female; –, no mutations found for FLT3, NPM1, cEBPa, WT, and IDH1; ND, not determined.