Table 2.
Prognostic Groups | Cytogenetics/Molecular | Efficiency of BM-MSC Culture Establishment | Mean Age (years) ± SD | Gender Ratio M/F | Mean Blasts (%) |
---|---|---|---|---|---|
LR-AML | inv(16)/CBFB-MYH11 | 3/3 (100%) | 44.4 ± 26.8 | 10/6 | 57.3 ± 24.8 |
t(8;21)/AML1-ETO | 1/1 (100%) | ||||
t(15;17)/PML-RARa | 2/3 (67%) | ||||
NK (NPMmut,FLT3wt) | 6/8 (75%) | ||||
t(5;15)/TP53BP1-PDGFRB | 1/1 (100%) | ||||
IR-AML | NK (NPMwt, FLT3wt, cEBPawt) | 10/11 (91%) | 55.2 ± 27.9 | 8/3 | 54.4 ± 24.5 |
HR-AML | CK | 7/7 (100%) | 59.7 ± 22.9 | 9/10 | 66.1 ± 25.9 |
NK (NPMwt,FLT3mut) | 4/5 (83%) | ||||
MLL-r (11q23) | 5/6 (83%) | ||||
NK/NPM1mut, IDH1mut | 1/1 (100%) | ||||
HD | 10/10 (100%) | 40 ± 8 | 6/4 | 0 |
NK, normal karyotype; CK, complex karyotype; MLL-r, MLL rearranged; MUT, mutated; HR, high risk; IR, intermediate risk; LR, low risk; HD, healthy donor.