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. 2017 Jun 13;17:90. doi: 10.1186/s12874-017-0364-y

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© The Author(s) 2017

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver(http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Simulated absolute values. Absolute values of differences were generated with 10000 simulation runs and with different models. Dashed lines represent the reference values, thus the differences between the values of the basic model and the values of the extended model in population data. GLM stands for generalized linear models, GAM for generalized additive models