Table 3.
Analysis of therapeutic interventions, complications and prognostic outcomes in patients with DNI
| Characteristic | ESRD-DNI | Non-ESRD-DNI | p-value | ||
|---|---|---|---|---|---|
| N | % | N | % | ||
| Total | 280 | 194 | |||
| Therapy | 0.394b | ||||
| antibiotic | 208 | 74.3 | 146 | 75.3 | |
| aspiration | 4 | 1.4 | 6 | 3.1 | |
| surgery | 68 | 24.3 | 42 | 21.7 | |
| Tracheostomy | 10 | 3.6 | 7 | 3.6 | 0.983c |
| Hospitalization (mean ± SD) | 11.1 ± 14.7 | 9.7 ± 12.7 | 0.269d | ||
| ICU care | 39 | 13.9 | 14 | 7.2 | 0.023c |
| Mediastinitis | 7 | 2.5 | 2 | 1.0 | 0.249c |
| Mediastinitis-Mortality | 3 | 1.1 | 1 | 0.5 | 0.515c |
| Mortalitya | 26 | 8.0 | 6 | 2.9 | 0.021c |
aMortality occurrence after DNI
bPearson’s chi-squared tests
cFisher exact tests
dStudent’s t tests
Abbreviations: SD standard deviation, ICU intensive care unit
Table 3 demonstrated the analysis of three therapeutic methods used for treatment of DNI, the indicators used for evaluating the interventions, complications and prognostic outcomes in both cohorts. There was no difference in the methods for treatment and the proportion of three therapies resembled in both cohorts. Tracheostomy rate, duration of hospitalization and mediastinal complication did not differ in both cohorts; however, the proportion of patients receiving ICU care was higher among those with ESRD and DNI. ESRD group had significantly higher mortality rate than non-ESRD group (p = 0.032)