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. 2017 Jun 9;8(6):1645–1658. doi: 10.1016/j.stemcr.2017.05.014

Figure 2.

Figure 2

Transposable Element Activation across the Pluripotent Spectrum

(A) Relative proportion of differentially expressed transposable element (TE) families between pairwise comparisons of all conditions.

(B) PCA showing the relationship between pluripotent states based on differential TE activation.

(C) Expression of selected LTR and LINE elements across the pluripotent continuum.

(D) Expression of the lncRNA Miat.

(E–G) Genome view showing RNA-seq tracks of detected chimeric transcripts that originate at an upstream LTR and splice to (E) Tcstv3, (F) Cyp2b23, and (G) Ash2l.

(H) Boxplots showing the median global DNA methylation (5-mC) level by bisulfite sequencing across various genomic features in the indicated culture condition and genetic background.

(I) Heatmap showing DNA methylation level at genomic imprints.