Figure 1. Patient Selection.

^aChemotherapy includes cabazitaxel, docetaxel, mitoxantrone hydrochloride, and estramustine.

^bCNS events include amnesia/memory impairment, anxiety, ataxia, cognitive disorders, confusion, convulsions, disturbance in attention, dizziness, falls, fatigue/asthenia, hallucinations, headaches, insomnia, pain, paresthesia, seizures, weakness, and other CNS disorders.

^cOther cancer diagnoses are identified with the following ICD-9-CM: 140.xx-184.xx, 186.xx–195.xx, 200.xx-209.xx.

CNS indicates central nervous system; ICD-9-CM, International Classification of Diseases, Ninth Revision, Clinical Modification.