TABLE 3.
Coinfections of mice with nonchemotactic and wild-type H. pyloria
| Exp (n) | Strain | Inoculum dose (input) (CFU) | Avg CFU/g of stomach (output) | Input ratio | Competitive index (output ratio/input ratio) |
|---|---|---|---|---|---|
| 1 (4) | cheW | 2.76 × 106 | 4.82 × 105 | 1.13 | 0.9 |
| cheA | 2.43 × 106 | 4.80 × 105 | |||
| 2 (5) | cheW | 2.5 × 107 | 1.8 × 105 | 1.39 | 0.3 |
| cheY | 1.8 × 107 | 4.26 × 105 | |||
| 3 (5) | Wild type | 1.8 × 107 | 3.6 × 106 | 0.3 | <0.001 |
| cheW | 5.3 × 106 | <100 | |||
| 4 (6) | Wild type | 1.32 × 107 | 4.07 × 106 | 2.26 | 0.009 |
| cheW | 2.98 × 107 | 8.1 × 104 | |||
| 5A (5) | Wild type | 2.53 × 107 | 2.42 × 106 | 2.39 | <0.001 |
| cheW | 6.05 × 107 | 616 | |||
| 5B (5) | Wild type | 2.53 × 107 | 2.86 × 106 | 0.8 | <0.001 |
| cheW | 2.02 × 107 | 188 | |||
| 5C (5) | Wild type | 2.53 × 107 | 2.16 × 106 | 0.27 | <0.001 |
| cheW | 6.7 × 106 | 1500 | |||
| 6 (4) | Wild type | 8.6 × 107 | 5.74 × 106 | 1 | 0.008 |
| cheY | 8.6 × 107 | 4.59 × 104 | |||
| 7 (4) | Wild type | 8.6 × 107 | 1.49 × 106 | 1.28 | 1.03 |
| cheY/complement | 1.1 × 108 | 1.96 × 106 |
a
Each strain listed under Strain was mixed and coinoculated into mice for 2-week infections. Competitive index is the output ratio (mutant/wild type) divided by the input ratio (mutant/wild type).