FIG. 6.

Adherence of Mφ to collagen matrices enhances PL fusion. Plastic- or collagen-adherent Mφ were labeled with HRP-Au18 and then incubated with C. albicans for 1 h at 37°C and then fixed and processed for electron microscopy. (Top) Electron micrograph showing a C. albicans yeast within the phagosome of a Mφ adherent to plastic. Note that there are numerous gold particles in the surrounding cytoplasm but none in the phagosome. (Bottom) Collagen-adherent Mφ with numerous gold particles within the yeast-containing phagosome. Bars, 1 μm.