Fig. 1.

(a) Representative mouse images showing the lifetime of a tumor region and an uninvolved skin region. A total of 5 mice with 14 tumors were analyzed. (b) Representative FLT decay showing a steep initial decay then a slower decay at longer times. (c) Average FLT long component for skin and tumor showing no difference. (d) Average FLT short component for skin and tumor showing a lower lifetime for the tumor, $p=0.004$. (e) Lifetime maps for each pixel for tumors and skin. Tumors exhibited shorter lifetimes with the more central region containing the shortest lifetimes. Tumor locations are indicated as left flank (LF), left shoulder (LS), right flank (RF), and right shoulder (RS). (f) Histogram of long lifetime component for each pixel showing no difference. (g) Histogram for short lifetime component showing that shorter values are unique to tumors. (h) ROC curve showing the sensitivity and specificity for tumor identification using different short lifetime thresholds (the data point labels).