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. 2017 Apr 18;317(15):1535–1543. doi: 10.1001/jama.2017.3417

Table 3. Time Away From Work or School, Medication Use, and Health Contactsa.

Total No. of Patients No. (%) of Patients Risk Difference, % (95% CI) Relative Risk (95% CI) P Value
Dexamethasone Placebo
Reconsultation at Health Care Facility
Overall 565 31/288 (10.8) 20/277 (7.2) 3.3 (−0.6 to 7.3) 1.48 (0.87 to 2.53) .15
No antibiotic prescription 342 23/173 (13.3) 16/169 (9.5) 3.5 (−3.1 to 10.0) 1.40 (0.77 to 2.56) .27
Delayed antibiotic prescription 223 8/115 (7.0) 4/108 (3.7) 3.2 (−1.8 to 8.2) 1.73 (0.54 to 5.50) .36
Patients Missing Work or Education
Overall 411 61/202 (30.2) 73/209 (34.9) −4.2 (−13.0 to 4.7) 0.86 (0.65 to 1.13) .26
No antibiotic prescription 254 32/123 (26.0) 39/131 (29.8) −3.1 (−14.0 to 7.8) 0.87 (0.59 to 1.30) .50
Delayed antibiotic prescription 157 29/79 (36.7) 34/78 (45.6) −6.2 (−21.3 to 8.9) 0.84 (0.58 to 1.23) .37
Antibiotics Consumed for Sore Throat
Overall 417 50/206 (24.3) 59/211 (28.0) −2.4 (−9.6 to 4.7) 0.83 (0.62 to 1.11) .22
No antibiotic prescription 260 16/127 (12.6) 17/133 (12.8) −0.2 (−8.3 to 7.9) 0.99 (0.52 to 1.87) .97
Delayed antibiotic prescription 157 34/79 (43.0) 42/78 (53.8) −10.8 (−26.4 to 4.7) 0.80 (0.58 to 1.11) .18
Antibiotics for Other Reasons
Overall 417 5/206 (2.4) 9/211 (4.3) −1.7 (−5.8 to 2.3) 0.58 (0.20 to 1.70) .32
No antibiotic prescription 260 5/127 (3.9) 6/133 (4.5) 0.1 (−4.5 to 4.8) 0.86 (0.27 to 2.73) .79
Delayed antibiotic prescription 157 0/79 3/78 (3.8)
Pain Relief Preparationsb
Overall 417 147/206 (71.4) 154/211 (73.0) −1.3 (−9.8 to 7.1) 0.98 (0.87 to 1.10) .77
No antibiotic prescription 260 88/127 (69.3) 98/133 (73.7) −4.4 (−15.3 to 6.6) 0.94 (0.81 to 1.09) .42
Delayed antibiotic prescription 157 59/79 (74.7) 56/78 (71.8) 3.2 (−10.1 to 16.6) 1.05 (0.88 to 1.25) .62
a

Log-binomial model adjusted for center and delayed antibiotic prescription.

b

Analysis includes only participants who provided follow-up information on the name of antibiotics used, including lozenges, linctus, and sprays that contain a local anesthetic or anti-inflammatory.