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. 2017 Apr 10;74(4):411–418. doi: 10.1001/jamaneurol.2016.5192

Table 4. Effects of LT on Actigraphy-Derived Sleep and Wake Metrics.

Actigraphy Marker Mean (SD) P Value,
Group/
Condition/
Interaction
Baseline Postintervention (Week 4) P Value,
Group/
Condition/
Interaction
Postwashout (Week 6)
Bright LT Dim-Red LT Bright LT Dim-Red LT Bright LT Dim-Red LT
Sleep Period
Sleep onset latency, min 30.16
(36.05)
23.54
(21.45)
27.68
(22.43)
17.06
(13.04)
.43/.75/.03 20.82
(10.67)
16.88
(9.75)
.36/.73/.03
Total activity counts 7247.5
(7242.5)
8538.3
(9560.7)
8680.9
(7807.1)
7898.9
(4750.0)
.54/.002 8755.8
(7445.1)
7012.7
(4456.9)
.79/.61
Average activity counts 19.74
(15.21)
22.31
(18.58)
24.09
(20.05)
21.17
(11.91)
.65/.002 22.22
(14.86)
18.02
(11.38)
.93/.73
Sleep efficiency 74.85
(15.41)
75.94
(15.26)
74.65
(16.23)
79.32
(9.02)
.60/.23 76.64
(10.43)
81.06
(9.61)
.39/.06
Wake after sleep onset, min 38.53
(40.67)
43.21
(34.64)
44.31
(42.52)
43.37
(22.78)
.37/<.001 48.06
(43.07)
40.58
(28.02)
.71/.45/.003
Sleep time, min 310.05
(72.49)
327.49
(87.11)
310.92
(82.14)
322.35
(66.48)
.49/.33 317.78
(51.63)
334.32
(58.79)
.49/.05
Average light/illuminance, lux 4.13
(8.35)
1.46
(2.40)
10.41
(32.89)
7.47
(25.30)
.04/.21 1.43
(2.09)
0.75
(0.94)
.02/.03
Maximum light/highest illuminance, lux 51.30
(41.39)
39.89
(56.95)
87.71
(180.37)
26.66
(27.84)
.24/.11/.02 34.57
(33.53)
16.71
(13.91)
.008/.26
Wake Period
Total activity counts 164 847
(71 139)
180 818
(64 901)
189 413
(88 824)
189 676
(47 246)
.59/<.001 170 951
(90 948)
184 419
(47 372)
.49/.01
Average activity counts 165.01
(66.87)
185.15
(56.63)
194.59
(87.81)
194.09
(47.35)
.39/<.001/.02 173.70
(89.08)
183.97
(43.43)
.51/.007
Sleep time, min 385.72
(145.76)
290.78
(82.84)
344.09
(103.68)
302.19
(109.43)
.06/.24 340.53
(114.14)
345.29
(136.13)
.45/.69
% Scored total sleep time 38.85
(14.58)
32.18
(10.16)
34.99
(10.61)
30.12
(9.80)
.12/<.001 37.61
(13.56)
32.29
(9.78)
.15/.07
Average light/illuminance, lux 507.42
(445.48)
304.74
(337.10)
706.49
(717.92)
314.82
(505.38)
.01/<.001/.002 569.81
(511.67)
236.20
(234.39)
.00/<.001
Maximum light/highest illuminance, lux 23 870
(13 716)
14 539
(13 134)
24 509
(13 189)
13 291
(17 333)
.004/.001 23 637
(14 272)
14 451
(12 564)
.008/.004/.03

Abbreviation: LT, light therapy.