Table 2. Distribution of Etiologic Stroke Subtypes by Classification System.
| Subtype | No. (%) | P Value | ||||
|---|---|---|---|---|---|---|
| CCS | TOAST | ASCO | CCS vs TOAST | CCS vs ASCO | TOAST vs ASCO | |
| Large-artery atherosclerosis | 395 (22) | 197 (11) | 353 (19) | <.001 | .09 | <.001 |
| Cardiac embolism | 443 (24) | 441 (24) | 449 (25) | .92 | .82 | .75 |
| Small-artery occlusion | 234 (13) | 113 (6) | 139 (8) | <.001 | <.001 | .09 |
| Uncommon causes | 149 (8) | 113 (6) | 105 (6) | .02 | .004 | .58 |
| Undetermined causes | 595 (33) | 952 (53) | 770 (42) | <.001 | <.001 | <.001 |
Abbreviations: ASCO, A for atherosclerosis, S for small-vessel disease, C for cardiac source, and O for other cause; CCS, Causative Classification of Stroke; TOAST, Trial of Org 10172 in Acute Stroke Treatment.