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. 2016 Dec 2;21(12):1661. doi: 10.3390/molecules21121661

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© 2016 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).

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Effects of the Janus compounds on cell cycle distribution. HeLa cells were treated with (A) vehicle (DMSO), or (B–G) the compounds indicated for 18 h and then the DNA was stained with propidium iodide and cell cycle distribution evaluated by flow cytometry. (H) The concentration-dependent effects of compounds 1–4 on the percentage of cells in G₂/M.