Table 2. Factors Associated With Minimal Risk in the Final Derivation Model^a.

Factor	Odds Ratio (95% CI)b	P Value	χ2
Age (per 5-y decrease)	1.55 (1.45-1.66)	<.001	173.9
Female sex	2.66 (2.17-3.25)	<.001	90.0
Racial or ethnic minority	1.07 (0.87-1.31)	.54	0.4
No hypertension	1.44 (1.20-1.73)	<.001	15.5
No dyslipidemia	1.48 (1.23-1.79)	<.001	17.1
Never smokerc	1.80 (1.51-2.15)	<.001	41.8
No family history of CAD	1.36 (1.13-1.65)	.001	10.3
No diabetes	1.50 (1.18-1.92)	.001	10.6
Symptoms unrelated to physical or mental stress (reference group: Yes)		.006	10.2
No	1.35 (1.12-1.63)
Unknown	1.20 (0.89-1.62)
HDL-C (per 5-point increase)	1.04 (1.01-1.07)	.02	5.3

Abbreviations: CAD, coronary artery disease; HDL-C, high-density lipoprotein cholesterol.

^a Model derivation C statistic = 0.730; model validation C statistic = 0.713.

^b Odds ratios greater than 1.00 indicate increased probability of minimal risk for every 5-unit increase or decrease in continuous variables and when comparing category shift in categorical variables.

^c Compared with ever smoking.