A, Progression-free survival (PFS). In total, 179 of 413 patients (43.3%) experienced a PFS failure: 19 of 38 (50.0%) in the non–cetuximab-treated KRAS-variant group, 13 of 32 (40.6%) in the cetuximab-treated KRAS-variant group, 74 of 169 (43.8%) in the non–cetuximab-treated nonvariant group, and 73 of 174 (42.0%) in the cetuximab-treated nonvariant group. B, Overall survival. In total, 134 of 413 patients (32.4%) have died: 14 of 38 (36.8%) in the non–cetuximab-treated KRAS-variant group, 8 of 32 (25.0%) in the cetuximab-treated KRAS-variant group, 58 of 169 (34.3%) in the non–cetuximab-treated nonvariant group, and 54 of 174 (31.0%) in the cetuximab-treated nonvariant group.