Table 1.
Performance of patient JAM on language, communication, speech fluency and repetition tasks at baseline, two endpoints and two washout evaluations.
| Measures | Baseline (Wk 0) | DP-10 mg (Wk 16) | DP-10/SLT (Wk 28) | Washout-1 (Wk 36) | Washout-2 (Wk 44) |
|---|---|---|---|---|---|
| (A) Language and communication | |||||
| Western Aphasia Battery (WAB) | |||||
| Aphasia Quotient (max = 100) | 79.6 | 88.3 | 90.0 | 87.7 | 84.5 |
| Fluency (max = 10) | 8 | 9 | 9 | 9 | 9 |
| Comprehension (max = 10) | 8.5 | 9.25 | 9.4 | 8.75 | 8.95 |
| Repetition (max = 10) | 6 | 7.4 | 7.8 | 7.7 | 8.4 |
| Naming (max = 10) | 8.9 | 9.5 | 9.8 | 9.4 | 6.4 |
| Communicative Activity Log, total | 112 | 149 | 156 | 158 | 158 |
| Frequency | 54 | 76 | 76 | 77 | 77 |
| Quality | 59 | 73 | 80 | 81 | 81 |
| (B) Speech fluency in connected speech | |||||
| WAB – Picture description | |||||
| Number of elements described | 14 | 18 | 20 | 18 | 18 |
| Number of words | 95 | 156 | 150 | 200 | 136 |
| Number of words/minute | 76 | 108 | 104 | 94 | 110 |
| Time (seconds) | 75 | 86 | 104 | 128 | 74 |
| Correct information units (CIU) | 59 | 144 | 109 | 126 | 105 |
| % CIU | 51 | 92 | 73 | 63 | 77 |
| CIU/minute | 38 | 100 | 76 | 59 | 85 |
| (C) Repetition of words and sentences | |||||
| Word repetition (n = 80) (PALPA 9) | 69 | 75 | 75 | 78 | 79 |
| Sentences (PALPA 12) | 8 | 11 | 12 | 10 | 11 |
| Idiomatic sentences (clichès) (max = 40) | 8 | 9 | 23 | 21 | 13 |
| Novel sentences (max = 40) | 9 | 14 | 28 | 24 | 20 |