FIG. 3.

Increased infiltration of gingiva with TLR2- and TLR4-positive cells in persons with CP. Interproximal gingival tissues from subjects with gingival health and those with disease (CP) were single-immunoenzyme labeled as described in Materials and Methods and analyzed by image-enhanced histomorphometry. (A) Shown are the mean number of immunoreactive cells/20× field; error bars indicate standard errors. Asterisks indicate a statistically significant increase in diseased versus healthy tissue by Student's t test (P < 0.05). (B and C) Linear-regression analysis of the number of TLR2⁺ (B) and TLR4⁺ (C) cells with the number of H&E-positive inflammatory cells.