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. Author manuscript; available in PMC: 2017 Nov 1.
Published in final edited form as: HIV Clin Trials. 2016 Sep 23;17(6):225–232. doi: 10.1080/15284336.2016.1234222

Table 2.

EPC changes over twelve weeks of telmisartan therapy.

Median # per 105 PBMC (IQR)
Total Absolute EPCs Week 0 Week 6 6-Week Fold Change p Week 12* 12-Week Fold Change p
Glycophorin/CD133+/KDR+ 8.0
(2.7, 112.4)
82.8
(11.3, 188.2)
1.8 0.02 89.2
(17.6, 159.9)
1.7 0.08
CD34+/CD133+ 33.3
(13.4, 85.5)
67.2
(31.6, 121.8)
1.4 0.06 87.6
(31.2, 128.5)
1.8 0.006
CD34+/KDR+ 1.8
(0.8, 49.6)
39.5
(2.0, 85.2)
1.9 0.08 45.9
(4.1, 77.6)
1.9 0.03
CD34+/CD133+/KDR+ 0.9
(0.3, 48.0)
38.5
(1.6, 83.9)
2.0 0.04 44.1
(3.0, 74.6)
2.0 0.02
Within CD34+ EPC Subset % of CD34+ EPC (IQR)
CD133+ 34.9
(32.5, 46.4)
37.6
(31.7, 43.1)
1.0 0.91 36.4 (25.3, 41.7) 1.0 0.83
KDR+ 5.9
(1.7, 17.4)
14.8
(2.6, 26.0)
1.5 0.11 14.5
(4.9, 20.8)
1.4 0.43
CD133+/KDR+ 4.2
(0.4, 15.2)
14.4
(2.4, 25.4)
1.7 0.07 14.1
(3.1, 19.8)
1.6 0.29
*

One subject excluded for increasing statin dose between weeks 6 and 12

12 subjects off drug

EPC= Endothelial Progenitor Cells, IQR=Interquartile Range, PBMC= Peripheral Blood Mononuclear Cells