TABLE 3.

Functional families overrepresented in the macrophage transcriptional response to treatment with Salmonella lipopolysaccharide (500 ng/ml)

Induced			Repressed
Biological process	P		Biological process	P
Cell growth	8.9 E-8		Mitotic cell cycle, S phase	4.5 E-8
Regulation of cell cycle	5.2 E-7		Regulation of cell cycle	4.3 E-7
Lymph gland development	1.0 E-5		Cytokinesis	1.3 E-5
Regulation of apoptosis	2.0 E-5		Lipid metabolism	8.0 E-5
DNA repair	9.2 E-5		Cell motility	3.2 E-4
Immune response	1.9 E-4		Protein phosphorylation	2.1 E-4
Angiogenesis	2.7 E-4		Mitotic cell cycle, M phase	7.5 E-4
Regulation of transcription	4.5 E-4		Endocytosis	0.0032
Intracellular signaling cascade	2.6 E-4		Apoptosis	0.0233
Cell differentiation	0.0021		Protein folding	0.0074
Amine metabolism	0.0026		Regulation of transcription	0.0031
Cell proliferation	0.0055		Intracellular signaling cascade	0.0066
Stress response (to pathogen/DNA damage/wounding)	0.0130