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. Author manuscript; available in PMC: 2017 Jun 14.
Published in final edited form as: Cell Rep. 2016 Mar 3;14(10):2426–2439. doi: 10.1016/j.celrep.2016.02.040

Figure 3. Global Impact of Autophagy Impairment on Basal Degradation Rates.

Figure 3

(A) Distribution of protein half-lives and degradation rates in WT, WT+vector, ATG5−/−, and ATG7−/− cells.

(B)Distribution of differences in degradation rates (Δkdeg) between WT+vector cells, and ATG5−/−, ATG7−/−, and WT cells.

(C) Pairwise comparisons of protein degradation rates in WT, WT+vector, ATG5−/−, and ATG7−/− cells. Black lines indicate identity lines, and red lines indicate best-fit lines to the proteome-wide data.